An intensive approach to treatment for older patients with relapsed isolated NPM1 mutated AML
نویسندگان
چکیده
We present a short case series of elderly patients with NK-AML and isolated NPM1 mutation who were treated with intensive chemotherapy, achieving significant CRs multiple times on reinduction, even with a single course.We hope to highlight the NPM1 as a molecular marker in elderly for consideration of aggressive treatment, even if abridged, as this subset may achieve a durable, good quality responses at diagnosis or subsequent relapses.
منابع مشابه
AML with mutated NPM1 carrying a normal or aberrant karyotype show overlapping biologic, pathologic, immunophenotypic, and prognostic features.
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2015